Be Experimental Tots Science Labs Lanarkshire

Transcranial direct current stimulation (tDCS) is a non-invasive method of stimulation that uses electrodes placed on the scalp to deliver a constant, low current. This study is being done to examine how tDCS affects the brain, and if brain changes are related to changes in mood. To see how tDCS affects brain signals, this study will use MRI scans. To make sure that changes are because of tDCS and not for other reasons, people will be randomized (assigned by chance) to receive either active or non-active (sham) tDCS using standard or small (high definition, HD) electrodes. This means if you agree to participate, you might not receive active experimental tDCS. You will be told at the end of the study if this is the case. If you did not receive active tDCS during the research, you will be invited to receive the same number of active tDCS sessions after the study. You may decide or not decide to receive these additional active tDCS sessions after your research participation is complete. We aim to enroll 100 patients who have depression and who have not made any changes to current medication(s) for the past six weeks.