During this on-demand session tutor Dr Nikki Osborne discusses: * What research integrity is, and who is responsible for what? * the research framework as it relates to the responsible use of live animals or animal derived materials in Life Science research, * good practice expectations regarding openness and transparency, plus the dissemination of research outputs, * real-life examples of research misconduct within the life science sector, plus common non-compliance issues with UK and EU legislation governing the use of animals in scientific procedures. * freely available tools and resources to support individuals to develop their knowledge, understanding and skills further.
During this on-demand session tutor Dr Nikki Osborne discusses: * what is welfare, the five freedoms & 'a life worth living' * why animal welfare is important - scientifically & ethically * how our understanding of a good life for laboratory animals is changing, * the laboratory animal's lifetime experience, * what refinement requires in practice & factors to consider, * sources of laboratory animals, plus husbandry & care, * the importance of good animal handling & knowing what is 'normal', * experimental procedures & assessing welfare, * humane endpoints & methods of killing * the refinement loop & marginal gains. * freely available tools and resources to support individuals to develop their knowledge, understanding and skills further.
During this on-demand session tutor Dr Nikki Osborne discusses: * the historical context for animal use in research, * the range of Societal viewpoints on the use of animals in research and ethical theories unpinning them, * how animal use in scientific procedures legislation takes into account 'social ethics' through the process of ethical review, * the 3Rs principles of humane experimental technique. * freely available tools and resources to support individuals to develop their knowledge, understanding and skills further.
During this on-demand session tutor Dr Nikki Osborne discusses: * the 3V's (construct, internal and external validity), * what makes a good hypothesis, * the PREPARE guidelines, * what to think about before designing your experiments including systematic reviews, * sources of bias and how to minimise their impact on your research, * defining the experimental unit, * approaches to maximise the signal to noise ratio, plus calculating the correct sample size, * common sources of variation and how to take them into account in your experimental design, * ARRIVE 2.0 for reporting animal studies. * freely available tools and resources to support individuals to develop their knowledge, understanding and skills further.
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